Réaction #75142

Équation de réaction

1-(3-chloropropyl)-1,3-dihydro-3-(1-methylethenyl)-2H-benzimidazol-2-one

hydrochloric acid

→

1-(3-chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one

Rendement 90.0%

Solvants

ethanol

Conditions de réaction

Traitement

1. 1
   AutreThe reaction mixture is evaporated
2. 2
   Autrethe solid residue is crystallized from 2-propanol

Mode opératoire

A solution of 13 parts of 1-(3-chloropropyl)-1,3-dihydro-3-(1-methylethenyl)-2H-benzimidazol-2-one in 6 parts of a hydrochloric acid solution and 40 parts of ethanol is stirred for 2 hours at room temperature. The reaction mixture is evaporated and the solid residue is crystallized from 2-propanol, yielding 9.5 parts (90%) of 1-(3-chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one; mp. 115° C.

Source