Réaction #74817

ord-2d77b27380a64c0eac7c4d81e8d5f37f

Équation de réaction

CN[C@@H](CC(C)C)C(=O)O
N-methyl-L-leucine
C[C@H](N)C(=O)O
L-alanine
CC(C)C[C@@H](C(=O)O)N(C)C(=O)CCSC(=O)c1ccccc1
N-(3-benzoylthiopropanoyl)-N-methyl-L-leucine
CC(C)C[C@H](N)C(=O)O
L-leucine
→
CC(C)C[C@@H](C(=O)O)N(C)C(=O)CCS
N-(3-mercaptopropanoyl)-N-methyl-L-leucine

Réactifs

CN[C@@H](CC(C)C)C(=O)O
N-methyl-L-leucine
C[C@H](N)C(=O)O
L-alanine
CC(C)C[C@@H](C(=O)O)N(C)C(=O)CCSC(=O)c1ccccc1
N-(3-benzoylthiopropanoyl)-N-methyl-L-leucine
CC(C)C[C@H](N)C(=O)O
L-leucine

Réactifs

Aucun

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Traitement

  1. 1
    Autreare obtained

Mode opératoire

By substituting N-methyl-L-leucine for the L-alanine in the procedure of Example 1, and then treating the product by the procedure of Example 2, N-(3-benzoylthiopropanoyl)-N-methyl-L-leucine, and N-(3-mercaptopropanoyl)-N-methyl)-L-leucine are obtained.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US04173704uspto-grants-1979_11