Réaction #742244
ord-4bada835d65a4d73ba88e933bd63e29b
Équation de réaction
(carbethoxyethylidene)triphenyl phosphorane
salicylaldehyde
→
(E)-3-(2-Hydroxy-phenyl)-2-methyl-acrylic acid ethyl ester
Réactifs
Aucun
Conditions de réaction
Conditions détaillées
See reaction.notes.procedure_details.
Traitement
- 1Températurewhile cooling in an ice-bath
- 2Lavagewashed
Mode opératoire
To a solution of 75.0 g (carbethoxyethylidene)triphenyl phosphorane in 350 ml of toluene, 23.2 g of salicylaldehyde was dropped in at 20° C. while cooling in an ice-bath. After stirring at room temperature for 90 mn., the reaction mixture was diluted with toluene and washed to neutrality with water.