Réaction #729823

Équation de réaction

6-Fluoro-9-naphthalen-1-ylmethyl-4,9-dihydro-pyrano[3,4-b]indole-1,3-dione

piperidine

→

title compound

5-Fluoro-1-naphthalen-1-ylmethyl-3-(2-oxo-2-piperidin-1-yl-ethyl)-1H-indole-2-carboxylic acid

Conditions de réaction

Mode opératoire

6-Fluoro-9-naphthalen-1-ylmethyl-4,9-dihydro-pyrano[3,4-b]indole-1,3-dione (from example 34.1.) was ring opened with piperidine at 22° C. to give the title compound as a white solid. MS: 445.4 ([M+H]+).

Source