Réaction #704854

Équation de réaction

2-pentanol

Thionyl chloride

4-acetoxy-2-fluoro-benzoic acid

→

4-acetoxy-2-fluoro-1-(1-methylbutyloxycarbonyl)benzene

Solvants

pyridine

Conditions de réaction

Traitement

1. 1
   Autreto react
2. 2
   Températureunder reflux for 7 hours
3. 3
   workup.DISTILLATIONThen, excessive thionyl chloride was distilled off

Mode opératoire

Thionyl chloride in an amount of 60 ml was added to 10.8 g (0.06 mol) of 4-acetoxy-2-fluoro-benzoic acid, and the mixture was allowed to react under reflux for 7 hours. Then, excessive thionyl chloride was distilled off, and then 10 ml of pyridine and 3.5 g (0.0402 mol) of 2-pentanol were dropwise added.

Source