Réaction #696695

Équation de réaction

1,4-diaminobutane

triethylamine

2-chloro-2-methyl-3-nitrosopentane

→

2-(4-aminobutyl)amino-2-methyl-3-pentanone oxime

Solvants

acetonitrile

acetonitrile

Conditions de réaction

Traitement

1. 1
   Autreto precipitate
2. 2
   workup.STIRRINGThe reaction mixture was stirred overnight
3. 3
   Filtrationthe product was filtered off
4. 4
   Autredried in vacuo
5. 5
   Autreto give a white powder, (0.5 g; 86%)

Mode opératoire

To a stirred solution of 1,4-diaminobutane (0.26 g; 2.9 mmol) and triethylamine (0.33 g; 3.2 mmol) in acetonitrile (5 ml) was added a solution of 2-chloro-2-methyl-3-nitrosopentane (0.485 g; 3.24 mmol) in acetonitrile (5 ml). After stirring for ca 10 minutes the product began to precipitate. The reaction mixture was stirred overnight and the product was filtered off and dried in vacuo to give a white powder, (0.5 g; 86%).

Source