Réaction #6901

ord-6fe6e3cc88c24bf59c2bd7d84afa2c25

Équation de réaction

Cc1cc2cc([N+](=O)[O-])ccc2nc1Cl
product
Cc1cc2cc([N+](=O)[O-])ccc2nc1Cl
2-chloro-3-methyl-6-nitroquinoline
CCN
ethylamine
CO
methanol
→
CCNc1nc2ccc([N+](=O)[O-])cc2cc1C
N-ethyl-3-methyl-6-nitroquinolin-2-amine

Réactifs

Cc1cc2cc([N+](=O)[O-])ccc2nc1Cl
product
Cc1cc2cc([N+](=O)[O-])ccc2nc1Cl
2-chloro-3-methyl-6-nitroquinoline
CCN
ethylamine
CO
methanol

Réactifs

Aucun

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Traitement

  1. 1
    Autreto prepare the product

Mode opératoire

The product (1 g, 4.5 mmol) from Step A and a solution of 2N ethylamine in methanol (5 mL, 25 mmol) were used to prepare the product according to the procedure of Example 1, Step C.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US07084156B2uspto-grants-2006_08