Réaction #684981

Équation de réaction

Trifluoroacetic acid

(4-(dodecanoylsulfamoyl)benzyl)carbamic acid tert-butyl ester

→

trifluoroacetic salt

Rendement 128.9%

4-Aminomethyl-N-(dodecanoyl)benzenesulfonamide

Rendement 128.9%

Solvants

dichloromethane

Conditions de réaction

Traitement

1. 1
   Autrewas at room temperature
2. 2
   AutreThe solvents were removed in vacuo
3. 3
   workup.DISSOLUTIONThe residue was dissolved in dichloromethane (40 ml)
4. 4
   Autrethe solvent was removed in vacuo

Mode opératoire

Trifluoroacetic acid (25 ml) was at room temperature added to a solution of (4-(dodecanoylsulfamoyl)benzyl)carbamic acid tert-butyl ester (170 mg, 0.40 mmol) in dichloromethane (25 ml). The reaction mixture was stirred for 1 h at room temperature. The solvents were removed in vacuo. The residue was dissolved in dichloromethane (40 ml) and the solvent was removed in vacuo. The latter procedure was repeated once to give 0.19 g of the trifluoroacetic salt of 4-aminomethyl-N-(dodecanoyl)benzenesulfonamide.

Source