Réaction #684948

Équation de réaction

Thionyl chloride

4-n-butylbenzyl alcohol

→

title compound

Rendement 104.9%

1-(Chloromethyl)-4-n-butylbenzene

Rendement 104.9%

Solvants

ether

Conditions de réaction

Traitement

1. 1
   AutreAfter concentration of the mixture, excess thionyl chloride was removed by azeotropic distillation with benzene

Mode opératoire

Thionyl chloride (2.5 ml, 34 mmol) was added to a solution of 4-n-butylbenzyl alcohol (2.0 g, 12 mmol) in ether (25 ml), and this mixture was stirred at room temperature for 3 hours. After concentration of the mixture, excess thionyl chloride was removed by azeotropic distillation with benzene to give the title compound (2.3 g). This compound was used in the following reaction without purification.

Source