Réaction #674328

ord-ca544ee631f9440493d3ef460bcd2779

Équation de réaction

NS(=O)(=O)Cc1cccc(Nc2ncnc(N3CCCCC3)n2)c1
B1
NS(=O)(=O)Cc1cccc(Nc2ncnc(N3CCCCC3)n2)c1
3-[(4-(Piperidin-1-yl)-1,3,5-triazin-2-yl)amino]benzenemethane sulfonamide
NS(=O)(=O)Cc1cccc(Nc2ncnc(Cl)n2)c1
A1
NS(=O)(=O)Cc1cccc(Nc2ncnc(Cl)n2)c1
3-[(4-Chloro-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide
C1CNCCN1
piperazine
→
NS(=O)(=O)Cc1cccc(Nc2ncnc(N3CCNCC3)n2)c1
3-[(4-(piperazin-1-yl)-1,3,5-triazin-2-yl)amino]benzenemethane sulfonamide

Réactifs

NS(=O)(=O)Cc1cccc(Nc2ncnc(N3CCCCC3)n2)c1
B1
NS(=O)(=O)Cc1cccc(Nc2ncnc(N3CCCCC3)n2)c1
3-[(4-(Piperidin-1-yl)-1,3,5-triazin-2-yl)amino]benzenemethane sulfonamide
NS(=O)(=O)Cc1cccc(Nc2ncnc(Cl)n2)c1
A1
NS(=O)(=O)Cc1cccc(Nc2ncnc(Cl)n2)c1
3-[(4-Chloro-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide
C1CNCCN1
piperazine

Réactifs

Aucun

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Traitement

  1. 1
    AutreB11 was prepared

Mode opératoire

B11 was prepared following the procedure reported for B1 using A1 and piperazine. MS (ES) C14H19N7O2S requires: 349. found: 350 (M+H)+.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US09226929B2uspto-grants-2016_01