Réaction #6662
ord-4dd019e84355481ab7d6cab2142e4e33
Équation de réaction
Triiodomesitylene
potassium permanganate acetic anhydride acetic acid sulfuric acid
→
triacetate
Rendement 35.0%
Réactifs
Aucun
Conditions de réaction
Conditions détaillées
See reaction.notes.procedure_details.
Mode opératoire
Triiodomesitylene is converted under acetylating conditions in an oxidation reaction with potassium permanganate/acetic anhydride/acetic acid/sulfuric acid into triacetate (yield: 35%). The triacetate is isolated and saponified with potassium carbonate in methanol to tris alcohol (yield: 94%). The tris alcohol is then reacted to form tris aldehyde by Swern oxidation in dimethyl sulfoxide as a solvent in a yield of 67%.