Réaction #66015

ord-2e759cf44ca14ab4bd25a591553de319

Équation de réaction

C=CC=O
acrolein
C=CC(=O)O
acrylic acid
O=C(O)/C=C/CC(=O)O
trans glutaconic acid
C=CC=O
acrolein
C=CC(=O)O
acrylic acid
O=C(O)/C=C/C(=O)O
fumaric acid
→
C=CC=O
acrolein
C=CC(=O)O
acrylic acid
O=C(O)/C=C\C(=O)O
maleic acid

Réactifs

C=CC=O
acrolein
C=CC(=O)O
acrylic acid
O=C(O)/C=C/CC(=O)O
trans glutaconic acid
C=CC=O
acrolein
C=CC(=O)O
acrylic acid
O=C(O)/C=C/C(=O)O
fumaric acid

Réactifs

Aucun

Solvants

CO
methanol

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Traitement

  1. 1
    Autrepurged with nitrogen, 10.55 g benzoyl peroxide
  2. 2
    workup.ADDITIONwas added
  3. 3
    Températureheated
  4. 4
    Températureto reflux under nitrogen for 75 h
  5. 5
    Autrewas dried under vacuum at 50-100° C. for 24 hours

Mode opératoire

Invented drug (acrolein:acrylic acid:trans glutaconic acid (mol)=80:15:5): 29.20 g freshly distilled acrolein, 200.22 g freshly distilled acrylic acid and 20.16 g fumaric acid were added into a three-port flask with 800 ml absolute methanol, purged with nitrogen, 10.55 g benzoyl peroxide was added, and the solution was stirred and heated to reflux under nitrogen for 75 h. The reaction solution became a yellowish viscous liquid, which was dried under vacuum at 50-100° C. for 24 hours to form to Poly (acrolein, acrylic acid, maleic acid) with an average molecular weight no less than 1000.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US08524216B2uspto-grants-2013_09