Réaction #65424

Équation de réaction

methyl 3-hydroxy-4-phenylthiobenzoate

potassium carbonate

dimethyl sulfate

→

methyl 3-methoxy-4-phenylthiobenzoate

Solvants

acetone

Conditions de réaction

Traitement

1. 1
   workup.ADDITIONwas added
2. 2
   Températurethe mixture was refluxed for 6 hours
3. 3
   TempératureThe reaction mixture was cooled
4. 4
   Filtrationthe precipitate was filtered
5. 5
   Lavagewashed with acetone
6. 6
   LavageThe filtrate and washing liquid
7. 7
   Concentrationconcentrated in vacuo

Mode opératoire

To a mixture of 49.11 g of methyl 3-hydroxy-4-phenylthiobenzoate, 27.33 g of potassium carbonate and 627 ml of acetone, 17.85 ml of dimethyl sulfate was added, and the mixture was refluxed for 6 hours while stirring. The reaction mixture was cooled, and the precipitate was filtered and washed with acetone. The filtrate and washing liquid were combined, and concentrated in vacuo, and methyl 3-methoxy-4-phenylthiobenzoate was obtained.

Source