Réaction #654181

ord-00bd1af3804e464ca9716b9613743df7

Équation de réaction

O=C1OC(=O)c2ccc([N+](=O)[O-])c3cccc1c23
4-Nitro-1,8-naphthalic anhydride
Cl.NO
hydroxylamine hydrochloride
→
O=C1c2cccc3c([N+](=O)[O-])ccc(c23)C(=O)N1O
title compound
Rendement 72.4%
O=C1c2cccc3c([N+](=O)[O-])ccc(c23)C(=O)N1O
2-Hydroxy-6-nitro-benzo[de]isoquinoline-1,3-dione
Rendement 72.4%

Réactifs

O=C1OC(=O)c2ccc([N+](=O)[O-])c3cccc1c23
4-Nitro-1,8-naphthalic anhydride
Cl.NO
hydroxylamine hydrochloride

Réactifs

Aucun

Solvants

c1ccncc1
pyridine

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Traitement

  1. 1
    AutreThe crude product was recrystallized from ethanol

Mode opératoire

4-Nitro-1,8-naphthalic anhydride (2.61 g, 10.7 mmol) and hydroxylamine hydrochloride (1.5 g, 21.4 mmol) were reacted in pyridine (50 mL) following the procedure of Example 1. The crude product was recrystallized from ethanol to give 2.0 g of the title compound, mp 255-260° C.;

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US06177423B1uspto-grants-2001_01