Réaction #65266

Équation de réaction

2-n-butyl-1-(2-chlorophenyl)methyl-1H-imidazol-5-carboxaldehyde

N-bromosuccinimide

→

2-(1-bromobutyl)imidazole

Solvants

carbon tetrachloride

Conditions de réaction

Traitement

1. 1
   Autrewas irradiated

Mode opératoire

A mixture of 2-n-butyl-1-(2-chlorophenyl)methyl-1H-imidazol-5-carboxaldehyde and N-bromosuccinimide in carbon tetrachloride was irradiated to give the 2-(1-bromobutyl)imidazole which was dehydrobrominated by treating 1,8-diazabicyclo[4.5.0]undec-1-ene in tetrahydrofuran to give 2-(1-butenyl)-1-(2-chlorophenyl)methyl-1H-imidazol-5-carboxaldehyde.

Source