Réaction #65060

Équation de réaction

Sodium cyanide

4-chlorobenzenediazonium tetrafluoroborate

→

4-Chlorobenzonitrile

Rendement 75.0%

Solvants

water

water

Conditions de réaction

Traitement

1. 1
   workup.STIRRINGstirred until it
2. 2
   Autreto react at room temperature
3. 3
   ExtractionThe mixture was extracted by ethyl acetate
4. 4
   Autrehad been formed in 75% yield

Mode opératoire

Sodium cyanide (2.94 g; 0.06 mol) was added to water and stirred. Cuprous cyanide (2.7 g; 0.03 mol) was added to the mixture stirred until it became homogeneous. 4-chlorobenzenediazonium tetrafluoroborate (5.66 g; 0.025 mol) in water (10 ml) was added to one portion. The mixture was allowed to react at room temperature. The mixture was extracted by ethyl acetate and the extract analysed by means of gas chromatography which indicated that 4-chlorobenzonitrile had been formed in 75% yield.

Source