Réaction #64300

Équation de réaction

3-amino-1,2,5-thiadiazole hydrochloride

ethyl 2-methyl-3,4,6,-trifluorobenzoylacetate

ethyl orthoformate

acetic anhydride

→

Ethyl 3-(1,2,5-thiadiazole-3-ylamino)-2-(2-methyl-3,4,6-trifluorobenzoyl)acrylate

Conditions de réaction

Traitement

1. 1
   Autre157 (colorless needles) was prepared in a similar manner to Example 17

Mode opératoire

Compound No. 157 (colorless needles) was prepared in a similar manner to Example 17, proceeding from the corresponding compounds ethyl 2-methyl-3,4,6,-trifluorobenzoylacetate, ethyl orthoformate, acetic anhydride and 3-amino-1,2,5-thiadiazole hydrochloride.

Source