Réaction #63460

ord-9f07261beadd4f4bb6d0226538e98cf2

Équation de réaction

CS(=O)(=O)N1CCOc2ccc(C3=NNC(=O)CC3)cc21
6-(3,4-Dihydro-4-methanesulfonyl-1,4(2H)-benzoxazin-6-yl)-2,3,4,5-tetrahydropyridazin-3-one
C=CCBr
allyl bromide
→
C=CCN1N=C(c2ccc3c(c2)N(S(C)(=O)=O)CCO3)CCC1=O
6-(3,4-Dihydro-4-methanesulfonyl-1,4(2H)-benzoxazin-6-yl)-2,3,4,5-tetrahydro-2-(2-propenyl)pyridazin-3-one

Réactifs

CS(=O)(=O)N1CCOc2ccc(C3=NNC(=O)CC3)cc21
6-(3,4-Dihydro-4-methanesulfonyl-1,4(2H)-benzoxazin-6-yl)-2,3,4,5-tetrahydropyridazin-3-one
C=CCBr
allyl bromide

Réactifs

Aucun

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Traitement

  1. 1
    AutreThe title compound was recovered

Mode opératoire

6-(3,4-Dihydro-4-methanesulfonyl-1,4(2H)-benzoxazin-6-yl)-2,3,4,5-tetrahydropyridazin-3-one was reacted with allyl bromide instead of methyl iodide, following the procedure of Example 9. The title compound was recovered, yield 2.03 g, mp 153°-155° C.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US04766118uspto-grants-1988_08