Réaction #62307

Équation de réaction

7-fluoro-3-[(E)-2-(pyridin-3-yl)-vinyl]-1H-indazol-5-ylamine

2-furancarboxylic acid

→

title compound

Rendement 37.9%

Furan-2-carboxylic acid{7-fluoro-1-(furan-2-carbonyl)-3-[(E)-2-(pyridin-3-yl)-vinyl]-1H-indazole-5-yl}-amide

Rendement 37.9%

Conditions de réaction

Traitement

1. 1
   Autrewith the method of Example 127, purification by LC-MS

Mode opératoire

Following amidation using 217 mg of 7-fluoro-3-[(E)-2-(pyridin-3-yl)-vinyl]-1H-indazol-5-ylamine and 286 mg of 2-furancarboxylic acid in accordance with the method of Example 127, purification by LC-MS was carried out, to afford 143 mg of the title compound as yellow crystals.

Source