Réaction #61835

Équation de réaction

1-(naphth-1-yl)-1-propanone

phenyltrimethylammonium tribromide

→

2-bromo-1-(naphth-1-yl)-1-propanone

Rendement 175.6%

Solvants

tetrahydrofuran

Conditions de réaction

Traitement

1. 1
   Autrethen partitioned between petroleum ether and aqueous sodium carbonate solution
2. 2
   AutreThe organic layer was separated
3. 3
   Lavagewashed with water, brine
4. 4
   Séchagedried with sodium sulphate
5. 5
   Filtrationfiltered
6. 6
   Autreevaporated in vacuo

Mode opératoire

To a solution of 1-(naphth-1-yl)-1-propanone (4.0 g) in anhydrous tetrahydrofuran (50 ml) was added phenyltrimethylammonium tribromide (8.0 g). The resulting mixture was stirred overnight at room temperature then partitioned between petroleum ether and aqueous sodium carbonate solution. The organic layer was separated, washed with water, brine, dried with sodium sulphate, filtered and evaporated in vacuo to yield crude 2-bromo-1-(naphth-1-yl)-1-propanone (5.7 g).

Source