Réaction #607419
ord-9d2883a823344f2ab5316f3decc835cf
Équation de réaction
2-amino-2-(4-bromophenyl)ethanol
3-(4-isothiocyanatophenyl)-1-(4-(trifluoromethyl)phenyl)-1H-1,2,4-triazole
→
title compound
1-(1-(4-Bromophenyl)-2-hydroxyethyl)-3-(4-(1-(4-(trifluoromethyl)phenyl)-1H-1,2,4-triazol-3-yl)phenyl)thiourea
Réactifs
Réactifs
Aucun
Conditions de réaction
Conditions détaillées
See reaction.notes.procedure_details.
Mode opératoire
The title compound was prepared with 2-amino-2-(4-bromophenyl)ethanol and 3-(4-isothiocyanatophenyl)-1-(4-(trifluoromethyl)phenyl)-1H-1,2,4-triazole and isolated as a white solid (1.56 g, 99%): 1H NMR (400 MHz, CDCl3) δ 8.72 (s, 1H), 8.32-8.22 (m, 2H), 7.92 (d, J=8.0 Hz, 2H), 7.82 (d, J=8.4 Hz, 2H), 7.45-7.28 (m, 8H), 7.20 (d, J=8.0 Hz, 1H), 5.69 (s, 1H), 4.11-3.86 (m, 2H); ESIMS m/z 562 ([M+H]+).