Réaction #60236

Équation de réaction

N,N′-dimethylethylenediamine

diphenylamine

4-bromoiodobenzene

→

white crystal

Rendement 70.2%

4-bromotriphenylamine

Rendement 70.2%

Solvants

xylene

Conditions de réaction

Traitement

1. 1
   Températurerefluxed for 24 hours under argon atmosphere
2. 2
   Filtrationthe mixture was filtered
3. 3
   Autreto remove an insoluble matter
4. 4
   Concentrationthe filtrate was concentrated

Mode opératoire

N,N′-dimethylethylenediamine 1.76 g was added to diphenylamine 16.9 g, 4-bromoiodobenzene 28.2 g sodium t-butoxide 14.4 g, copper powder 3.81 g and a xylene 100 ml solution, and the mixture was heated and refluxed for 24 hours under argon atmosphere. After cooled down to room temperature, the mixture was filtered to remove an insoluble matter, and the filtrate was concentrated. The residue was refined by silica gel chromatography to obtain 22.7 g of white crystal of 4-bromotriphenylamine.

Source