Réaction #59788

Équation de réaction

4-(2-methyl-imidazole-1-sulfonyl)-piperazine-1-carboxylic acid tert-butyl ester

trifluoromethanesulfonic acid methyl ester

→

4-(2-methyl-imidazole-1-sulfonyl)-piperazine-1-carboxylic acid tert-butyl ester triflate salt

Solvants

methylene chloride

Conditions de réaction

Traitement

1. 1
   Autrethe solvent was evaporated

Mode opératoire

A solution of 4-(2-methyl-imidazole-1-sulfonyl)-piperazine-1-carboxylic acid tert-butyl ester (1.4 g, 4.24 mmol) in methylene chloride was cooled in an ice bath, and trifluoromethanesulfonic acid methyl ester (0.56 mL, 4.9 mmol) was added via a pipet. After stirring at ice temperature for 3 h, the solvent was evaporated to give 4-(2-methyl-imidazole-1-sulfonyl)-piperazine-1-carboxylic acid tert-butyl ester triflate salt as yellow solids.

Source