Réaction #57818

Équation de réaction

(2-amino-4,5-difluoro-phenyl)-pyridin-3-yl-methanone

4-bromo-benzenesulfonyl chloride

→

title compound

4-Bromo-N-[4,5-difluoro-2-(pyridine-3-carbonyl)-phenyl]-benzenesulfonamide

Solvants

pyridine

Conditions de réaction

Traitement

1. 1
   AutrePurification on silica gel with flash column chromatography
2. 2
   Autreyielded light orange solid

Mode opératoire

The title compound was prepared according to the general procedures for the synthesis of N-Aryl-benzenesulfonamides previously described using (2-amino-4,5-difluoro-phenyl)-pyridin-3-yl-methanone 1 g (4.27 mmol) and 4-bromo-benzenesulfonyl chloride 1.15 g (4.27 mmol) with stirring in 20 ml pyridine. Purification on silica gel with flash column chromatography yielded light orange solid

Source