Réaction #56581

Équation de réaction

2,3,5-Triiodobenzoyl chloride

1-(z,z,z-octadeca-6,9,12-trienoyloxy)-3-hydroxypropane

triethylamine

→

1-(2,3,5-triiodobenzoyloxy)-3-(z,z,z-octadeca-6,9,12-trienoyloxy)propane

Solvants

methylene chloride

Conditions de réaction

Traitement

1. 1
   ConcentrationThe mixture was concentrated
2. 2
   Autrepurified by flash chromatography (ethyl acetate/hexane)

Mode opératoire

2,3,5-Triiodobenzoyl chloride (1.54 g, 3.08 mmol) was added to a mixture of 1-(z,z,z-octadeca-6,9,12-trienoyloxy)-3-hydroxypropane (1 g, 2.97 mmol) and triethylamine (1 ml) in methylene chloride (80 ml) and the resulting mixture stirred overnight at room temperature under nitrogen. The mixture was concentrated and purified by flash chromatography (ethyl acetate/hexane) to yield 1-(2,3,5-triiodobenzoyloxy)-3-(z,z,z-octadeca-6,9,12-trienoyloxy)propane.

Source