Réaction #56343

ord-05ced917aa254317b64d4bc091a33dff

Équation de réaction

O=C1NC(=O)C(c2ccccc2)(c2ccccc2)N1.[Na]
sodium diphenylhydantoin
COC(=O)CCCCBr
methyl 5-bromovalerate
→
O=C1N=C(O)NC1(c1ccccc1)c1ccccc1
Diphenylhydantoin

Réactifs

O=C1NC(=O)C(c2ccccc2)(c2ccccc2)N1.[Na]
sodium diphenylhydantoin
COC(=O)CCCCBr
methyl 5-bromovalerate

Réactifs

Aucun

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Traitement

  1. 1
    Autrefollowed by acid hydrolysis
  2. 2
    Autreto yield the following: ##STR15##

Mode opératoire

Following the method of Cook et al, Res. Comm. Chem. Path. Pharm. 5:767(1973), sodium diphenylhydantoin is reacted with methyl 5-bromovalerate followed by acid hydrolysis to yield the following: ##STR15##

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US04225485uspto-grants-1980_09