Réaction #55783

Équation de réaction

2-hydroxymethylpyrimidine

3-mercaptopropylamine

methylamine

2-[(3-aminopropyl)thiomethyl]-pyrimidine

→

N-cyano-N'-methyl-N"-[3-(2-pyrimidylmethylthio)propyl]guanidine

Conditions de réaction

Mode opératoire

Also, reacting 2-hydroxymethylpyrimidine with 3-mercaptopropylamine by the procedure of Example 1 and then reacting the resulting 2-[(3-aminopropyl)thiomethyl]-pyrimidine with dimethyl-N-cyanoimidodithiocarbonate and methylamine by the procedure of Example 3(d) gives N-cyano-N'-methyl-N"-[3-(2-pyrimidylmethylthio)propyl]guanidine.

Source