Réaction #55647

Équation de réaction

3-(4-hydroxyphenyl)glutaric acid

acetic anhydride

→

3-(4-acetyloxyphenyl)glutaric anhydride

Conditions de réaction

Traitement

1. 1
   Autreevaporated to dryness in vacuo
2. 2
   AutreThe residual solid is crystallized from chloroform-hexane

Mode opératoire

A solution of 3-(4-hydroxyphenyl)glutaric acid (800 mg) in acetic anhydride (15 ml) is heated at 100° C. for 2.5 hours and evaporated to dryness in vacuo. The residual solid is crystallized from chloroform-hexane to afford 600 mg of 3-(4-acetyloxyphenyl)glutaric anhydride, melting point 140°-143° C.

Source