Réaction #55599

Équation de réaction

5-(2-Chloro-4-trifluoromethylphenoxy)-2-nitrobenzoic acid

triethanolamine

→

Tris-(2-hydroxyethyl)ammonium 5-(2-Chloro-4-trifluoromethylphenoxy)-2-nitrobenzoate

Solvants

glyme

glyme

Conditions de réaction

Traitement

1. 1
   workup.STIRRINGAfter stirring for a few hours the solvent
2. 2
   Autreis removed in vacuo
3. 3
   Autrethe product is triturated repeatedly with petroleum ether (bp 30°-60° C.)
4. 4
   Autredried to a weight of 2.5 g

Mode opératoire

5-(2-Chloro-4-trifluoromethylphenoxy)-2-nitrobenzoic acid (3.0 g, 0.0083 mole) is dissolved in glyme (20 ml) and a solution of triethanolamine (1.35 g, 0.0091 mole) in glyme (5 ml) is added rapidly while stirring at room temperature. After stirring for a few hours the solvent is removed in vacuo, the product is triturated repeatedly with petroleum ether (bp 30°-60° C.) and dried to a weight of 2.5 g.

Source