Réaction #554599

Équation de réaction

boron boron tribromide

water

2-methoxytriphenylene

→

2-hydroxytriphenylene

Rendement 95.1%

Solvants

methylene chloride

methylene chloride

Conditions de réaction

Traitement

1. 1
   Températurewhile increasing temperature of the reaction solution to room temperature
2. 2
   Filtrationfollowed by filtration
3. 3
   LavageThe resulting solid was washed with water and methanol

Mode opératoire

Under an argon atmosphere, 13.9 g of 2-methoxytriphenylene was placed in a flask, and 300 mL of methylene chloride was added. The reaction solution was cooled to −78° C., and 54 mL of a solution of 1M boron boron tribromide in methylene chloride was dropwise added thereto. The reaction solution was stirred for 5 hours while increasing temperature of the reaction solution to room temperature. 100 mL of water was added to the reaction solution, followed by filtration. The resulting solid was washed with water and methanol to obtain 12.5 g (yield: 95%) of 2-hydroxytriphenylene.

Source