Réaction #55108

Équation de réaction

2-amino-4-hydroxymethylimidazole hydrochloride

picrate

hydrochloric acid

cysteamine hydrochloride

2-amino-4-[(2-aminoethyl)thiomethyl]imidazole

methyl isothiocyanate

→

N-methyl-N'-[2-((2-amino-4-imidazolyl)methylthio)ethyl]thiourea

Conditions de réaction

Traitement

1. 1
   Autreis obtained

Mode opératoire

Reaction of 2-amino-4-hydroxymethylimidazole hydrochloride (which is obtained by treating the picrate salt with hydrochloric acid) with cysteamine hydrochloride and reaction of the resulting 2-amino-4-[(2-aminoethyl)thiomethyl]imidazole with methyl isothiocyanate by the methods of Example 1 gives N-methyl-N'-[2-((2-amino-4-imidazolyl)methylthio)ethyl]thiourea.

Source