Réaction #54944

Équation de réaction

4-Methyl-1,5-octadiyn-4(RS)-ol

dihydropyran

p-toluenesulfonic acid

→

4-methyl-4(RS)-tetrahydropyran-2-yloxy-1,5-octadiyne

Solvants

benzene

Conditions de réaction

Mode opératoire

4-Methyl-1,5-octadiyn-4(RS)-ol is reacted with dihydropyran in the presence of p-toluenesulfonic acid in dry benzene to provide 4-methyl-4(RS)-tetrahydropyran-2-yloxy-1,5-octadiyne which in turn is reacted with triethyl tin hydride to provide 4-methyl-4(RS)-tetrahydropyran-2-yloxy-oct-5-yn-trans-1-enyl triethyl tin, having the following structural formula: ##STR12##

Source