Réaction #548661

ord-e128f60000ba484d87be01489aa5d34b

Équation de réaction

[Mg+2].[O-][O-]
magnesium dioxide
Cc1cccc(C(=O)O)c1Cl
2-Chloro-3-methylbenzoic acid
B#B
diborane
Cc1cccc(CO)c1Cl
2-chloro-3-methylbenzyl alcohol
Cc1cccc(C=O)c1Cl
2-chloro-3-methylbenzaldehyde

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

2-Chloro-3-methylbenzoic acid was reduced by treating with diborane in tetrahydrofuran and the resulting 2-chloro-3-methylbenzyl alcohol was oxidized with activated magnesium dioxide in methylene chloride to give 2-chloro-3-methylbenzaldehyde.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US04062961uspto-grants-1977_12