Réaction #54289

Équation de réaction

3-(4-chlorobenzoyl)-benzeneacetic acid

thionyl chloride

→

3-(4-chlorobenzoyl)-benzeneacetic acid chloride

Conditions de réaction

Traitement

1. 1
   Températureto reflux
2. 2
   Autreexcess thionyl chloride was removed under reduced pressure
3. 3
   workup.DISSOLUTIONThe residue was dissolved in benzene
4. 4
   Autrethe solution was evaporated to dryness under reduced pressure
5. 5
   workup.DISSOLUTIONThe residue was dissolved in 50ml of anhydrous benzene

Mode opératoire

A solution of 8.235 g of 3-(4-chlorobenzoyl)-benzeneacetic acid in 20 ml of thionyl chloride was heated to reflux and then excess thionyl chloride was removed under reduced pressure. The residue was dissolved in benzene and the solution was evaporated to dryness under reduced pressure. The residue was dissolved in 50ml of anhydrous benzene to obtain a solution of 3-(4-chlorobenzoyl)-benzeneacetic acid chloride which was used as is for the next step.

Source