Réaction #53824

ord-664aa3c04c5a4769afcb66fc186f71c0

Équation de réaction

CN(C(=O)Oc1ccc(Cl)cc1)[C@H]1CC[C@H](O)CC1
trans-(4-Hydroxy-cyclohexyl)-methyl-carbamic acid 4-chloro-phenyl ester
BrCCCCCBr
1,5-dibromopentane
→
CN(C(=O)Oc1ccc(Cl)cc1)[C@H]1CC[C@H](OCCCCCBr)CC1
trans-[4-(5-Bromo-pentyloxy)-cyclohexyl]-methyl-carbamic acid 4-chloro-phenyl ester

Réactifs

CN(C(=O)Oc1ccc(Cl)cc1)[C@H]1CC[C@H](O)CC1
trans-(4-Hydroxy-cyclohexyl)-methyl-carbamic acid 4-chloro-phenyl ester
BrCCCCCBr
1,5-dibromopentane

Réactifs

Aucun

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

In analogy to example 11.5, trans-(4-Hydroxy-cyclohexyl)-methyl-carbamic acid 4-chloro-phenyl ester and 1,5-dibromopentane were reacted to yield trans-[4-(5-Bromo-pentyloxy)-cyclohexyl]-methyl-carbamic acid 4-chloro-phenyl ester as yellow oil, MS: 433 (MH+, 1Br, 1Cl).

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US06858651B2uspto-grants-2005_02