Réaction #53544

ord-e365b54716bb493cbf42c13966c41724

Équation de réaction

Nc1ccc(-c2nc3ccccc3s2)cc1Cl
2-(4′-amino-3′-chlorophenyl)benzothiazole
NCCCC[C@H](N)C(=O)O
lysine
C[C@H](N)C(=O)O
alanine
→
Cl.Cl.Nc1ccc(-c2nc3ccccc3s2)cc1Cl.[NH-]C(=O)[C@@H](N)CCCCN
title compound
Cl.Cl.Nc1ccc(-c2nc3ccccc3s2)cc1Cl.[NH-]C(=O)[C@@H](N)CCCCN
2-(4′-Amino-3′-chlorophenyl)benzothiazole Lysyl Amide Dihydrochloride Salt

Réactifs

Nc1ccc(-c2nc3ccccc3s2)cc1Cl
2-(4′-amino-3′-chlorophenyl)benzothiazole
NCCCC[C@H](N)C(=O)O
lysine
C[C@H](N)C(=O)O
alanine

Réactifs

Aucun

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

The title compound was prepared using the method of Example 22 but with 2-(4′-amino-3′-chlorophenyl)benzothiazole instead of 2-(4′-aminophenyl)-benzothiazole and BOC protected lysine instead of BOC protected alanine.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US06858633B1uspto-grants-2005_02