Réaction #53493

ord-39a5f7da03d24d749f2c4900d49b0e3b

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Mode opératoire

The operation is carried out under the conditions described in Example 124 starting with 150 mg of activated 3-({1-[bis(4-chlorophenyl)methyl]azetidin-3-ylidene}methanesulfonylmethyl)benzoic acid on TFP resin (165 μM) and 0.0396 cm3 of 2-(aminomethyl)-N-ethylpyrrolidine. 58 mg of 3-({1-[bis(4-chlorophenyl)methyl]azetidin-3-ylidene}methanesulfonylmethyl)-N-(1-ethylpyrrolidin-2-ylmethyl)benzamide are thus obtained in the form of an ochre-colored foam.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US06858603B2uspto-grants-2005_02