Réaction #531803

Équation de réaction

4c

N-(Tris(3-benzyloxy-4-oxo-4H-pyran-2-yl)carboxyaminopropyl)methyl benzamide

→

title compound 6

Rendement 114.7%

N-(Tris(-3-hydroxy-4-oxo-4H-pyran-2-yl)carboxyaminopropyl)methyl benzamide

Rendement 114.7%

Solvants

acetic acid

hydrochloric acid

Conditions de réaction

Traitement

1. 1
   ConcentrationThe reaction mixture was concentrated in vacuo
2. 2
   Autrethe residue azeotroped several times with methanol (10 ml)

Mode opératoire

A solution of 4c (0.20 g, 0.20 mmol) in glacial acetic acid (2 ml) and concentrated hydrochloric acid (2 ml) was stirred at room temperature for 18 h. The reaction mixture was concentrated in vacuo, the residue azeotroped several times with methanol (10 ml) to afford the title compound 6 (130 mg, 90%) as a red-orange solid.

Source