Réaction #531791

Équation de réaction

Mercaptopropionic acid

Triphenylmethylchloride

→

3-(tritylthio)propionic acid

Rendement 95.7%

Solvants

methylene chloride

Conditions de réaction

Traitement

1. 1
   Autrewere carried out at room temperature
2. 2
   Filtrationwas gathered by filtration
3. 3
   Autrethe solid components obtained here
4. 4
   Autrewere dried under reduced pressure

Mode opératoire

Mercaptopropionic acid 12 (3.14 g) was dissolved in 50 ml of methylene chloride. Triphenylmethylchloride 13 (8.36 g) was added to that, and 19-hour reactions were carried out at room temperature. The precipitate generated through the reactions was gathered by filtration, and the solid components obtained here were dried under reduced pressure, to form 9.86 g of 3-(tritylthio)propionic acid 14, which is a white solid.

Source