Réaction #531736

Équation de réaction

β-alanine benzyl ester p-toluenesulfonate

ammonia

( 2 )

1-Methylthiomethyl-1H-tetrazole-5-thiol

1-benzyloxycarbonylmethyl-1H-tetrazole-5-thiol

glycine benzyl ester p-toluenesulfonate

→

1- (carbamoylmethyl)-1H-tetrazole-5-thiol

Conditions de réaction

Mode opératoire

The reactions described in Reference Example 10 (1) and (2) were carried out using glycine benzyl ester p-toluenesulfonate in lieu of β-alanine benzyl ester p-toluenesulfonate to prepare 1-benzyloxycarbonylmethyl-1H-tetrazole-5-thiol, which was then converted with alcoholic ammonia into the captioned compound.

Source