Réaction #51983

Équation de réaction

(1R)-2-(methylamino)-1-pyridin-2-ylethanol

3-chloroacetylpyridine

→

title compound

(1S)-2-(methylamino)-1-pyridin-3-ylethanol

Conditions de réaction

Mode opératoire

As described for the preparation of (1R)-2-(methylamino)-1-pyridin-2-ylethanol (Preparations 68-69), 3-chloroacetylpyridine (Chem. Ber. 1951, 84, 147-149) is converted to the title compound, isolated as a pale yellow amorphous solid.

Source