Réaction #51415

Équation de réaction

1,3-Dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one

isobutyl iodide

→

1,3-dihydro-1-isobutyl-5-phenyl-2H-1,4-benzodiazepin-2-one

Conditions de réaction

Mode opératoire

1,3-Dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one (prepared according to the procedure of M. G. Bock et al., J. Org. Chem. 1987, 52, 3232-3239) was alkylated with isobutyl iodide using General Procedure 8-G to afford 1,3-dihydro-1-isobutyl-5-phenyl-2H-1,4-benzodiazepin-2-one.

Source