Réaction #51388

ord-df73a96a3c1b46e181f22eba45d4f13e

Équation de réaction

O=C(O)Cc1cccc([N+](=O)[O-])c1
3-nitrophenylacetic acid
CCOC(=O)[C@@H](N)CCSC.Cl
methionine ethyl ester hydrochloride
→
CCOC(=O)[C@H](CCSC)NC(=O)Cc1cccc([N+](=O)[O-])c1
title compound
CCOC(=O)[C@H](CCSC)NC(=O)Cc1cccc([N+](=O)[O-])c1
N-[(3-nitrophenyl)acetyl]methionine ethyl ester

Réactifs

O=C(O)Cc1cccc([N+](=O)[O-])c1
3-nitrophenylacetic acid
CCOC(=O)[C@@H](N)CCSC.Cl
methionine ethyl ester hydrochloride

Réactifs

Aucun

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Traitement

  1. 1
    AutreThe reaction was monitored by tlc on silica gel and purification
  2. 2
    Autrewas by recrystallization from butyl chloride

Mode opératoire

Following General Procedure BG above and using 3-nitrophenylacetic acid (Aldrich) and methionine ethyl ester hydrochloride (Aldrich), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by recrystallization from butyl chloride.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US06849650B2uspto-grants-2005_02