Réaction #51359

ord-c9e4c34315f84686a3656f6cf4d21f12

Équation de réaction

O=C(O)Cc1cccc([N+](=O)[O-])c1
3-nitrophenylacetic acid
CCC(N)C(=O)OCC(C)C
iso-butyl 2-aminobutyrate
→
CCC(NC(=O)Cc1cccc([N+](=O)[O-])c1)C(=O)OCC(C)C
title compound
CCC(NC(=O)Cc1cccc([N+](=O)[O-])c1)C(=O)OCC(C)C
2-[(3-nitrophenyl)acetamido]butyric acid iso-butyl ester

Réactifs

O=C(O)Cc1cccc([N+](=O)[O-])c1
3-nitrophenylacetic acid
CCC(N)C(=O)OCC(C)C
iso-butyl 2-aminobutyrate

Réactifs

Aucun

Conditions de réaction

Conditions détaillées
See reaction.notes.procedure_details.

Traitement

  1. 1
    AutreThe reaction was monitored by tlc on silica gel and purification
  2. 2
    Filtrationwas by filtration

Mode opératoire

Following General Procedure BI above and using 3-nitrophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Source

DOI: 10.6084/m9.figshare.5104873.v1Brevet: US06849650B2uspto-grants-2005_02