Réaction #5129
ord-62caf7e77d574b0eacf847ea9cbf3833
Équation de réaction
1,12-bis(2-amino-3,4,5,6-tetrahydropyrimidyl)dodecane dihydroiodide
methanol water
→
guanidine
1,12-Bis(2-amino-3,4,5,6-tetrahydropyrimidyl)dodecane diacetate
Réactifs
Aucun
Conditions de réaction
Conditions détaillées
See reaction.notes.procedure_details.
Mode opératoire
30.0 g (0.048 mol) of 1,12-bis(2-amino-3,4,5,6-tetrahydropyrimidyl)dodecane dihydroiodide in 300 ml of methanol/water (1:1) were filtered through a column containing 250 g of ion exchanger (OH- form). The free guanidine base obtained after working up was dissolved in methanol and converted into the diacetate with excess glacial acetic acid.