Réaction #51230

Équation de réaction

N-(tert-butoxycarbonyl)piperazine

potassium carbonate

hydrochloric acid

butyl iodide

→

N-butylpiperazine.dihydrochloride

Solvants

dimethylformamide

Conditions de réaction

Traitement

1. 1
   Autrereaction

Mode opératoire

To a dimethylformamide (7 ml) solution containing N-(tert-butoxycarbonyl)piperazine (1.0 g) were added potassium carbonate (742 mg) and then butyl iodide (1.09 g), and the mixture was stirred at room temperature for 15 hours to undergo reaction, thereby obtaining N-tert-butoxycarbonyl-N-butylpiperazine. This compound was acid-treated with hydrochloric acid to obtain N-butylpiperazine.dihydrochloride.

Source