Réaction #502164
ord-cbfe5ed99dbd4ccb873ed01a5a53db2b
Équation de réaction
4-(methylsulphanyl)-6-oxo-2-(3-thienylmethyl)-1,6-dihydropyrimidine-5-carbonitrile
4-tert-butylpiperidine
→
title compound
4-[4-(tert-Butyl)piperidin-1-yl]-6-oxo-2-(3-thienylmethyl)-1,6-dihydropyrimidine-5-carbonitrile
Réactifs
Réactifs
Aucun
Conditions de réaction
Conditions détaillées
See reaction.notes.procedure_details.
Mode opératoire
In analogy to the preparation of Example 1, 100 mg (0.38 mmol) of 4-(methylsulphanyl)-6-oxo-2-(3-thienylmethyl)-1,6-dihydropyrimidine-5-carbonitrile are reacted with 536 mg (3.80 mmol) of 4-tert-butylpiperidine to give 57 mg (42% of theory) of the title compound.