Réaction #502158

Équation de réaction

4-(methylsulphanyl)-6-oxo-2-(3-thienylmethyl)-1,6-dihydropyrimidine-5-carbonitrile

n-propylamine

→

title compound

6-Oxo-4-(propylamino)-2-(3-thienylmethyl)-1,6-dihydropyrimidine-5-carbonitrile

Conditions de réaction

Mode opératoire

In analogy to the preparation of Example 1, 100 mg (0.38 mmol) of 4-(methylsulphanyl)-6-oxo-2-(3-thienylmethyl)-1,6-dihydropyrimidine-5-carbonitrile are reacted with 224 mg (3.80 mmol) of n-propylamine to give 14 mg (13% of theory) of the title compound.

Source