Réaction #502155
ord-955ceac335e74db39cb29b4888506fd5
Équation de réaction
2-(3-fluorobenzyl)-4-(methylsulphanyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile
cyclopentylamine
→
title compound
4-(Cyclopentylamino)-2-(3-fluorobenzyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile
Réactifs
Réactifs
Aucun
Conditions de réaction
Conditions détaillées
See reaction.notes.procedure_details.
Mode opératoire
In analogy to the preparation of Example 1, 100 mg (0.36 mmol) of 2-(3-fluorobenzyl)-4-(methylsulphanyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile are reacted with 309 mg (3.63 mmol) of cyclopentylamine to give 12 mg (11% of theory) of the title compound.