Réaction #502153
ord-d63653e7c1aa48258c90c62f468293d3
Équation de réaction
2-(4-chlorobenzyl)-4-(methylsulphanyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile
cyclobutylamine
→
title compound
2-(4-Chlorobenzyl)-4-(cyclobutylamino)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile
Réactifs
Réactifs
Aucun
Conditions de réaction
Conditions détaillées
See reaction.notes.procedure_details.
Mode opératoire
In analogy to the preparation of Example 1, 100 mg (0.34 mmol) of 2-(4-chlorobenzyl)-4-(methylsulphanyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile are reacted with 244 mg (3.43 mmol) of cyclobutylamine to give 15 mg (14% of theory) of the title compound.